![]() The levels of hypocretin are found to be low in many people who have narcolepsy, and it's been found that the body's ability to maintain a state of wakefulness is regulated by hypocretin. Hypocretin, also called orexins, are excitatory neuropeptide hormones. Length of attacks can range from up to a few seconds, less than two minutes, and up to 30 minutes. Furthermore, people can have slurred speech and impaired eyesight such as double vision and inability to focus. Examples of these emotions can be:įacial muscles, weakness at the knees and total collapse can occur in a cataplexy attack. ![]() It refers to the muscular weakness that is suddenly triggered by strong emotions. What is cataplexy?Ĭataplexy is a symptom of narcolepsy. Excessive daytime sleepiness is experienced but usually doesn't have muscle weakness triggered by emotions. Type 1 narcolepsy, which was previously known as narcolepsy with cataplexy, is where a patient either has low levels of hypocretin.Īlso called narcolepsy without cataplexy, Type 2 narcolepsy usually has less severe symptoms than Type 1 narcolepsy. The two main types of narcolepsy are Type 1 narcolepsy and Type 2 narcolepsy. This means the brain isn't as able to regulate sleep cycles. This protein is produced in the same area of the brain that creates hypocretin, resulting in a lack of hypocretin. It's been found that some people with narcolepsy produce antibodies, which are released by the body to destroy diseases and toxins, against the trib 2 protein. ![]() Infections, such as the swine flu or the flu vaccination medication against it, Pandemrix.Īnother cause could relate to immune system problems.Hormonal changes, either during puberty or the menopause.However, it's not always the case and sometimes causes are unclear. The most common cause of narcolepsy is the lack of hypocretin, the brain chemical that modulates the body's wakefulness. Automatic behaviour – doing an activity without having any memory of doing it afterwards.Hallucinations when going to sleep or waking up.Sleep paralysis – a sudden inability to move when falling asleep or waking up which generally lasts for a few minutes.Cataplexy – a sudden loss of strength and control in some muscles, resulting in slurred speech, a dropping head, and sometimes falls.What are the signs and symptoms of narcolepsy?Īs already mentioned, the most well-known symptom of narcolepsy is sleep attacks during the day. Most people who are diagnosed with narcolepsy are between 20 and 40 years old. The cause is not clear, but it’s thought that narcolepsy can be triggered by puberty, menopause, an infection, or major psychological stress. Narcolepsy is relatively rare, affecting just one in 2000 people, and affecting men and women equally. It’s a condition characterised by 'sleep attacks' during the day, where you suddenly fall asleep without control. Narcolepsy is a neurological condition which affects your brain’s control over when you sleep.
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![]() I feel like I’ve hit a stage in my life where I want to have a more well-rounded existence. The idea of starting all over again isn’t as exciting as it was when I was a little younger. I started my first business when I was 19, and I’ve been an entrepreneur for 15 years. Whether he would ever launch another new company: There is a lot of negativity out there, but the truth is that all great things start out with a great idea. His biggest piece of advice to aspiring entrepreneurs: It was such a special experience to do a collaboration with them.” Ralph Lauren, from a classic American style point of view, is a great company. He was doing social activist campaigns before it was cool, and I give him a lot of credit for using his brand to raise awareness of important issues. There have been a couple of times where I’ve been at a crossroads and I’ll call Kenneth and he says, ‘Let’s have breakfast and talk about it.’ He has a great soul. “Kenneth Cole has become a good friend and a good mentor. ![]() The ultimate dream would be for people to talk about Toms the way they talk about Patagonia.” They’re still a private company they haven’t gotten too big and they never took on investors. ![]() It keeps me focused on why we started and what we’re doing. Their founder, Yvon Chouinard, wrote a book called ‘Let My People Go Surfing,’ and I read that once a year. We played soccer for an hour, just me and the kids - no journalists, no photographers. I remember that as an athlete growing up, it was always exciting to get new gear or shoes, and now they got to experience that same joy of getting something that helped them do their sport better. But they wanted to show me how much better they were playing because of their new shoes. Instead of grass, there were rocks it was very rugged. I finally followed, and they took me to the back of their school, where there was a soccer field. “These three boys, even after they had their shoes, kept pulling on me to come with them. So I’ve been spending more time disappearing. Every time I get recognized at the airport or on the street, it’s cool, and I don’t want to take that for granted, but it’s also draining. “It’s funny, in the past 18 months, I’ve become much more introverted. “I don’t want it to be the Blake show,” he said. ![]() We’re a movement, not a company.”Īnd while Mycoskie is at the center of that movement, it isn’t always easy to be its very public brand ambassador. Most shoe companies would freak out and worry that they weren’t making money off that. You go to these campuses and the students have made T-shirts and flags, all kinds of things. “We really struck a chord with young consumers who want to incorporate giving into their personal identity,” said Mycoskie, who lives on a sailboat in Southern California and has shed many of his personal possessions. Mycoskie’s outreach has centered on college students, a group that has fueled the company’s rapid growth. “This customer is very socially aware, wants to make a difference and loves the brand.” “Our customers are passionate about Toms and believe in the mission of giving shoes to kids in need,” said Scott Meden, EVP and GMM for shoes at Nordstrom, which is launching children’s shoes with Toms next month. The company’s founding mission - to give away a pair of shoes for every pair it sells - has resonated strongly with both retailers and consumers. It’s been a whirlwind journey for the 34-year-old, who went on a trip to Argentina in early 2006 to learn polo and came back with the idea for Toms after noticing that most of the country’s children lacked shoes. “More than anything, I like teaching, so this is a way for me to expand on some of the lessons we’ve learned.” I write every day it’s part of my process,” said Mycoskie, who has been working on the book for about a year. “I’ve been keeping journals since I was 15. (Details couldn’t be divulged until the final edits are made.) In it, he details the rise of Toms and chronicles other successful social entrepreneurs. In between riding the waves, Mycoskie put the finishing touches on the first draft of his forthcoming, as-yet-untitled book, which will be published by Random House. There’s so much more to do,” Mycoskie said, two weeks before the shoe drop, during an exclusive interview in Montauk, N.Y., where he spent most of August “thinking, writing and surfing.” “From a business standpoint, this gives us legitimacy and says we’re here to stay. Da Brat Announces Pregnancy at 48 in Vintage Gangster-Inspired Suit, Bra & Lace-Up Brogues for Peopleįor Mycoskie, it’s still just the beginning. There would be less of a chance of leaving a blue trail. My second premise, while searching forĮxamples of hair styles, was that by having blue at the bottom fringe, that I wanted blue at the bottom part, based on my experience in the past twoīlue dye came off on my neck (hello, Smurf!), pillows and towels. In, the increased grey will blend nicely. My grand experiment this time is based on the premise thatīy dying the top part of my hair silver/grey, that when my natural hair grows An image found on Pinterest, showing off Silver Fox sexiness “silver fox” and making it as sexy for women as men. Women of a certain age have taken over the term Natural progression and not coloring their roots to young women coloring theirĭeclared silver as the hottest color for 20. Thankfully, in the past few years, grey has become the ![]() Transition time until my hair becomes completely grey? With letting my “roots” grow so long, it wasĮasier to see how the “sparkles” (as my former hair dresser called my grey)Ĭhange and becoming a nomad, what would be a good solution for that awkward Over the past few months I haven’t done much with my hair,Īs I paid more attention to downsizing and selling my house. The Silver Edition My hair, before, with long roots and lots of sparkles “Thanks!” I yelled back, and proceeded to walk home and goĪ look at myself from a stranger’s point of view, and letting go of all thoseĪnd the silver addition is my latest hair-venture. The texture felt dry, it was being too fluffy and making me look like a cocker Having one of those moments about my hair – the color seemed too blonde in spots, Telling you that you need commercial products because you are not perfect ![]() Let’s not even go into the how the whole beauty culture depends on Overall beauty of the person that is you. It’s so easy to look in the mirror and see the flaws instead of the Whether you want to let nature take its course, add highlights to match your roots, or make an instant transition to gray hair, here are tons of great ideas for rocking a stunning silvery style.A woman drove by me today and yelled out her car window “I love your hair!”Įver have one of those moments when you realize that how you And always protect your locks from the sun to prevent discoloration. Be sure to condition regularly, too, since gray hair is coarser than its pigmented counterparts. ![]() Opt for a gray hair shampoo or a purple shampoo, like Clairol Professional Shimmer Lights, which helps neutralize yellow, brassy tones and keeps your strands looking vibrant. You'll also want to protect your hair beyond the usual frizzy hair products. To make the transition between your gray roots and the rest of your hair more seamless, ask your stylist to add gray highlights and lowlights to your whole head. If you're going gray naturally and want to embrace it, you can either cut your hair short or wait six to 12 months while your roots grow out. After all, there are so many gorgeous gray hair color ideas out there, from dark silver to nearly white. Or, they're more interested in experimenting with colors beyond the usual suspects. Thinking of going gray? You're in good company! Thanks to the recent gray hair dye trend, more and more women are opting to go gray earlier than they might have a decade ago. John, who played Red Ranger Jason, told Entertainment Tonight. “Thousands of people tried out for the show,” Austin St. THE ACTORS WHO PLAYED THE RANGERS WERE FOUND IN OPEN CASTING CALLS. “She called me and said, ‘Why don’t you come in?’ So I went in and I got the job.” 5. she was casting Power Rangers in her office,” Johnson said. She had taken an acting class with Katy Wallin, who was also a casting director. He called my parents … and was like, ‘She really should come back.’” Then fate stepped in: “The night before I was moving, I met this man named Walter Rainey, who ended up being my acting coach for about 10 years after that,” she said. with her boyfriend, and they had broken up she had sold everything she owned and was moving back home. “ a little discouraged, a little lonely,” she told No Pink Spandex. Johnson’s first six months in Los Angeles were tough. In an interview with No Pink Spandex, Amy Jo Johnson, who played Pink Ranger Kimberly Hart, revealed that when they began filming, the show “was Dino Rangers at the time, when the show just started, before they changed the name to Power Rangers.” 4. Then he met with Fox Children’s Network president Margaret Loesch, who definitely was interested-and the rest is history. “For seven years I've schlepped this thing, and everyone said, 'Go take a pill or something,' because this is too weird-guys in spandex suits and dinosaurs,'' Saban said in 1993. It's so big in Japan, but nobody else around the world is looking at this stuff,’” Shuki Levy, the show's executive producer (who wrote and scored the pilot episode), told Complex.īut when Saban was shopping around the show around, no one was interested. “He said to me, ‘We gotta do something with this. On a trip to Japan to meet with animation studios, he discovered Super Sentai. IT TOOK SEVEN YEARS TO SELL THE SHOW.īefore he was the executive producer of Power Rangers, Haim Saban was a concert promoter, a theme song writer, and the producer of NBC’s Kidd Video (like MTV, but for children). According to the Los Angeles Times, Toei chose that theme “to ride on the dinosaur fever generated by Jurassic Park.” The characters and their likenesses were licensed to Saban Entertainment. Japanese kids got to watch Five Rangers Turbo Rangers Goggle Five Rangers Battle Fever J Rangers Ninja Rangers and King Rangers.Īmerica’s Power Rangers were based on the Beast Rangers of the Dinosaur Corps, the 16th version of Toei’s Rangers. The first iteration lasted two years, but afterward, the Rangers got a new theme every year. Super Sentai was created by Toei Studios in 1975. It’s morphin time! 1. IT WAS BASED ON A POPULAR JAPANESE SHOW. ![]() Here are a few things you might not have known about the original series. The original version of Mighty Morphin Power Rangers is still beloved by many, and will be getting a movie reboot in 2017. For three years in the mid-1990s, kids across the country tuned in every day but Sunday to watch five teenagers from Angel Grove transform into superheroes who defeated giant bad guys using dinosaur robots called Zords. ![]() The Best Dota 2 Wallpapers for Your PC in 2022 Every Dota 2 fan has favorite heroes or a favorite team. How well can you run DOTA 2 on a GTX 1080 720p, 1080p or 1440p on low, medium, high or max settings This data is noisy because framerates depend on several factors but the averages can be used as a reasonable guide. The result is high quality rendering at a lower performance cost than full resolution rendering, which allows for higher framerates even on less powerful graphics cards. You can see them not only in the game or stream, but also on your desktop. Watch Dotado 20 cm online HD 1080p - XVIDEOS. That’s why we decided to make it easier for you and collect all the amazing Dota 2 wallpapers in one place. JAV HD Pornhub Premium Xvideos Vjav xHamster Login. ![]() 720p Arlequina pela primeira vez em video com 2 amigos no motel - Casal Ninfos Prime 4 min. Players can enable this setting in the Video options by turning the "Game Screen Render Quality" to less than 100%, and then turning on the "FidelityFX Super Resolution" checkbox. ![]() FidelityFX Super Resolution works on any GPU compatible with DirectX 11 or Vulkan. Proxychains-ng YI Dome Camera 720p Dota 2 Proxy server ENCHANTREES, others, game, super, fictional Character. Truth be told, Dota 2 isn't exactly the most taxing game out there with its exceedingly low system requirements. In this video we take a look at some Dota 2 Gameplay on the 10 year old Nvidia GeForce GTX 260. Still, it's another game where you can test the new AMD FidelityFX Super Resolution spatial upscaling technique.ĪMD FSR 2. ![]() This is the only game in the series in which instead of one character per kart, there are two: one to drive, and one to use items and is also the first in the series where players drop their items when hit by a weapon. Some items, such as shells and bananas, allow the player to hit others to slow them down, while other items, such as the star power-up, render them temporarily invincible to attacks. Like in the previous installments, players can pick up item boxes to receive a randomly selected item and use it to impede the opposition and gain the advantage. The game screen indicates the current standings in a race, the current speed of the player's kart (as both numbers and coloured bars) and incoming weapons. Mario Kart: Double Dash!! is a kart racing video game in which 2 players race in a kart against other 2-player teams in 16 different courses. Two players can ride on a kart instead of one in Mario Kart: Double Dash!! See also: Gameplay of the Mario Kart series DK and Wario racing at Luigi Circuit, the first course of the game. It also was rereleased as a player’s choice title in Australia and New Zealand. ![]() ![]() ![]() It is the second best-selling GameCube game of all-time, selling around 7 million copies worldwide, behind Super Smash Bros. It was commercially successful, with more than 3.8 million copies sold in the United States, and more than 802,000 copies sold in Japan. Reviewers praised the graphics, new gameplay features, character and item rosters, arcade aesthetic and track design, but elements of the voice acting were poorly received. There are 20 characters to select from in total, each of which with a special item, and with eleven characters being new to the series.ĭouble Dash!! received positive reviews from critics it attained an aggregated score of 87 out of 100 on Metacritic. Double Dash!! supports LAN play using the Nintendo GameCube Broadband Adapter, allowing up to 16 players to compete simultaneously. Double Dash!! is the only game in the Mario Kart series to allow cooperative gameplay so far. One player drives the kart and the other uses items, hence the game's title. The game introduced a number of new gameplay features, such as supporting co-op gameplay with two riders per kart. Similar to the previous titles, Double Dash!! challenges Mario series player characters to race against each other on Mario-themed tracks. It is the first game in the series to use 3D polygon graphics for the racers, as opposed to sprites, after Mario Kart 64 only used polygons for the environments, and 2D sprites for the racers. This game is the fourth main entry in the Mario Kart series, succeeding Mario Kart: Super Circuit (2001). 2.Mario Kart: Double Dash!! is a 2003 kart racing video game developed and published by Nintendo for the GameCube. In Mario Kart Tour, there is a successor to the kart called the Waluigi Racer Mk. Likewise, the Waluigi Racer is quite bouncy while making jumps, which can greatly affect its speed on adverse terrain more than the other karts. The Waluigi Racer is also wider than other karts in its class, making it more vulnerable to oncoming items or ones lying about. Interestingly, when compared to all the other middleweight karts, the Waluigi Racer loses the least amount of speed whenever it goes off-road. In terms of its actual stats, while the Waluigi Racer's top speed is tied with that of the Red Fire, it shares the same acceleration as the Bloom Coach. It has a body style similar to a bike and looks similar to the Zipper from Mario Kart DS and The Duke from Mario Kart 8.Īccording to the game, the Waluigi Racer shares the same stats as the Red Fire, but it is actually slightly heavier than most other middleweight karts, being just as heavy as the Turbo Yoshi. The Waluigi Racer is colored purple and dark gray, with a pointed front resembling Waluigi's nose. It is a middleweight kart unlocked by completing the Flower Cup in 100cc. The Waluigi Racer is Waluigi's signature kart in Mario Kart: Double Dash!!. ![]() When it was heated and combined, I added the popcorn and stirred it for a couple of minutes until the popcorn was coated with the caramel mixture. Next, I made the “caramel” in another large pot (you can use a Dutch oven) by combining sugars butter, corn syrup (I made two recipes with light corn syrup and one with dark corn syrup), and salt (see actual recipe at the bottom of this post). You can use whatever kind of popcorn you’d like to use, but I think it is best if it is plain, unbuttered popcorn. ![]() Want to know how I made it? Watch and see.įirst, I made the popcorn by popping it on the stove in a big pot with a little oil. The resulting caramel corn from this recipe is softer and a tad chewy, but not overly or unpleasantly so. If you want a crisp, crunchy caramel corn, this recipe isn’t for you. It turned out really well! It also came together really fast and didn’t heat up my kitchen. ![]() I took my mom’s popcorn ball recipe and used that instead of a traditional caramel corn. Since I promised to make this yummy caramel corn for tonight, I had to find a substitute. The repairman ordered the necessary part to repair it, but it’s not getting installed until tomorrow. It broke a week and a half ago, and I’m suffering without it. All the recipes I found called for baking the caramel corn in the oven before drizzling it with chocolate. It’s a large group, so I decided to try my hand at making a knock off version. Well, our church youth group is having an activity tonight, and one of the young women I work with suggested having zebra popcorn as a treat. There’s a famous store in my local mall that sells “Zebra” popcorn, which, translated into English, is caramel coated popcorn with dark and white chocolate drizzled on top. ![]() These examples are programmatically compiled from various online sources to illustrate current usage of the word 'transistor.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. ![]() ![]() Michelle Delgado, Smithsonian Magazine, 3 Apr. Don Clark, New York Times, This walkie-talkie technology evolved further with the arrival of the transistor, a small device that amplifies electrical signals that are broadcast through a speaker, in 1948. David Hamilton, Fortune, 1 June 2023 That processor, intended to power another advanced supercomputer at Lawrence Livermore National Laboratory, has 146 billion transistors, compared with tens of billions for most advanced conventional chips. 2023 One of its recent products, the H100 GPU, packs in 80 billion transistors - about 13 million more than Apple’s latest high-end processor for its MacBook Pro laptop. Ashley Dunn, Los Angeles Times, 24 Mar. Patrick Moorhead, Forbes, Looking at a graph of chip development, Moore extended the line forward 10 years and predicted that by 1975 there would be 65,000 transistors on a single silicon chip. IEEE Spectrum, 12 June 2023 These teams aim to find the best-case scenario for power, performance and area (PPA), considering the billions of transistors that are all tightly packed into one die. tions defined by tables of zeros and ones. Jack Fitzgerald, Car and Driver, 21 June 2023 In the complex quest to keep increasing the density of transistors, extreme ultraviolet (EUV) lithography is the most critical tool. The basic unit of the computer revolution has changed inform. TTL ICs usually have four-digit numbers beginning with 74 or 54. Many TTL logic gate s are typically fabricated onto a single integrated circuit (IC). Palmer, New York Times, 12 July 2023 Hyundai's preliminary assessment leads it to believe that the problem stems from an over-current within the ICCU that can damage transistors in the 12V battery system, hampering its ability to recharge. transistor-to-transistor logic (TTL): Transistor-transistor logic (TTL) is a digital logic design in which bipolar transistor s act on direct-current pulses. Recent Examples on the Web Three firms, all located in the U.S., dominate the market for chip-design software, which is used to arrange the billions of transistors that fit on a new chip. ![]() The lyrics in AI’s re-written version of “Hey Jude” did evoke the same message as McCartney’s, but at the end of the day, it is Macca’s performance of this simple ballad that made it the iconic piece of art we know it as today. It’s a little meta but, we suppose it works. Instead of Hey Judey, Judey, Judey, Judey, ah the lyrics read Rewrite it, rewrite it, rewrite it, rewrite it. Even his intuitive ad-libs at the end of the song were accounted for in the new version. The lyrics trek on in the same spirit as McCartney’s original lines. If the child slaughter then come later Wrapped up and returned after many years Crawled out from under uncouth layers To take a shell back a. Let’s rewrite the story, rewrite it instead. I see a red door and I want it painted black No colors anymore I want them to turn black I see the girls walk by dressed in their summer clothes I have to turn my head until the darkness goes I see a line of cars and they're all painted black With flowers and my love both never to come back I see people turn their heads and quickly look away Like a new born. The AI version of the song was dedicated to someone named Alex ( Author’s note: which I’m trying not to freak out about given that my name is also Alex…how did it know?) and kept the original song’s narrative of hope amid a sticky situation. The third time was the charm, it seems, and the technology was able to come up with something original. More translations of Paint It Black lyrics. The second time it tried generating a re-written version of “Hey Jude,” it added the name “Lucy” in the place of “Jude” and then kept the lyrics exactly the same. The first time the technology tried generating a re-written version, it took out the name “Jude” and kept the lyrics exactly the same: Hey don’t make it bad. The Last Words lyrics: Gather around so I can tell you What will happen to you in days to come First you must paint all in black And pay with eyes - look. ![]() ![]() Turns out, getting AI to rewrite “Hey Jude” was more of a challenge than we expected. In a small OSPF network, imagine you have 1 datacenter and 20 branch offices. How we can adapt Einstein’s simplicity principle to networking ? If ‘A represents a process, and ‘A***’ represents the simplest possible version of ‘A’, then one should work towards finding ‘A***’, and not towards an intermediate version ‘A**’ or ‘A*.įrom this example, as you can understand, most possible simplicity is recommended by Einstein. It is very long debate what really Einstein was trying to say and unfortunately since He is dead, we can’t ask himself but at least let’s try to understand. ” Everything should be made as simple as possible, but no simpler ” Let’s remember What Einstein said about simplicity. By maintaining our other design principles of Trust, Clarify, Control, and Humanize, our users are able to leverage the intelligent engine for more areas of their work.What is KISS Principle ? Okay it stands for Keep it Simple and Stupid but what does really it mean in networking ?Ĭan we really make things simpler ?. We simplify the user experience whenever we can to allow the user to carry out their tasks with our AI-based products. This is a perfect example of KISS in action: The user has an option to apply or dismiss the recommendation, and a simple UI control that does not require prior knowledge of the intricate details of the algorithm’s technical details is working behind the scenes.īranding these “smart” inputs with a distinct CLAIRE color and appearance in various places further reinforces user’s awareness of these unique items. ![]() The reasoning behind the recommendation is provided in a short tooltip. Recommended stakeholders or tags are shown inside the input field, and visually branded to indicate that they are driven by the CLAIRE engine. Here’s an example of how we handled algorithm-driven recommendations for tags or stakeholder assignment in input fields: We apply these principles consistently throughout our design. We apply this stepped approach-using clear, understandable language-whenever we’re trying to explain tasks that cannot be briefly summarized. Instead, we present explanations in simple language that everyone can quickly understand.Īny complex idea can become a lot simpler when it’s broken down into smaller steps. When explaining AI decisions and rationale, we try to avoid using highly technical or scientific terms related to Artificial Intelligence or Machine Learning those terms would require prior knowledge and education. We use simple, one-sentence explanations to help our users quickly understand and decide on any actions related to AI-based features. We simplify by following a few Simple (J) guidelines:Ī picture is worth a thousand words, and that’s exactly the reason you want to avoid using images to explain a complex task. Applying KISSĪs Informatica products are built with the CLAIRE engine at their heart, it becomes a top priority for us to simplify the design of features that are expanding in back-end complexity. And even the most complex intelligent systems must still feel simple. In order to use them properly, the widest possible audience must be able to understand their output and effect on the user’s task. Highly complex in nature, AI and ML are perceived as a complete and untouchable black box by most users. When you think about it, AI and ML algorithms are an extreme example of the importance of the KISS principle. What’s true for fighter planes and mobile applications is especially true for Artificial Intelligence (AI-) and Machine Learning (ML-) powered features. The simpler the product or execution, the more likely it is that this output will be useful to the user. The end user doesn’t care how clever the creator is, they care about being able to use the output of this creativity, to make it useful to their own application. ![]() ![]() Decades later, this axiom applies, whether it’s conceptual physics, elaborate engineering, or consumer products. |
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